Zemgale is crossed by five national importance roads. The national importance roads A12 and A6 also include one of the longest West - East direction of the European international highway E22, which is also the Trans-European Transport Network (TEN-T). Road A7 direction to North-South incorporates into the European international line E67, but the A8 is a part of North - South direction of the European international motorway E77.
There are 28 state and regional roads and 237 local roads crossing Zemgale and road network density in Zemgale is better than average density in Latvia.
The region is crossed by several international railroads, pipelines - lines of oil products and gas pipelines.